The Gut-Brain Axis: How Microbes Influence Mood and Cognition

The gut and brain are deeply connected through what scientists call the gut-brain axis. This two-way communication system links the microbiome with the central nervous system, influencing mood, cognition, and even stress response.

Microbes as Neurotransmitter Factories

Gut microbes produce key neurotransmitters including serotonin, dopamine, and GABA. In fact, more than 90% of the body’s serotonin is produced in the gut. These compounds affect everything from sleep and appetite to mood regulation.

Impact on Mental Health

Research shows that imbalances in the gut microbiome are associated with conditions like anxiety, depression, and brain fog. A diverse and balanced microbiome, on the other hand, is linked to greater resilience and cognitive performance.

The Role of Bifidobacterium adolescentis

Human-native strains such as B. adolescentis have been studied for their ability to produce GABA, a calming neurotransmitter. By supporting gut balance and reducing inflammation, they may help regulate stress and promote a more stable mood.

Personalized Microbiome Care

Precision Prebiotics and targeted probiotics make it possible to strengthen the gut-brain axis by feeding the right microbes. Clinical studies suggest that improving gut health can have measurable effects on cognition, focus, and emotional well-being.

Leser T, et al. Bifidobacterium adolescentis – a beneficial microbe. Benef Microbes. 2023;14(6):525–551. doi:10.3920/BM2023.0031